I bought the 4 bottle pkg. (150ml each) and it is an excellent roxuct for me. I have had issues withinflamed skin around my stoma for years. Since starting to use Pure Cleanse during each ostomy bag change, the inflammation has disappeared. Put gauze (non-woven) over the inflamed area and soak it with Pure Cleanse. Leave it 10 - 15 minutes and clean the stea after using the gauze. Allow it to dry tbe I use a barrier wipe and then a barrier clinical adhesive spray, allowing it to dry before Putting your ostomy bag on, ensuring that all areas of the bag that have adhesive e are firmly attached to your skin. I use adhesive“wings” to reinforce the edges of the gasket to help prevent leaks. Thank you for making such an excellent product in ÑureCleNse, it has given me relief both physically and mentally. By the way the smaller 150 ml. bottle is better for packing in your suitcase.